Lose is a verb that means the opposite of “to win” or “to gain.”
The S is pronounced like a Z.
Lose the football game, lose 20 pounds of fat
Loose is usually an adjective that means the opposite of tight or bound.
The S is pronounced like a snake sound: SS.
Examples: The dog got loose from his leash.
His pants were so loose they nearly fell off.
However, “loose” can also be a verb meaning to let something loose or release. Sometimes it is used to mean the same thing as “loosen,” which means to make less tight.
Loose the homing pigeons!
You need to take a vacation and loosen up a bit.